In some advanced cases of diabetes, nerve damage, called diabetic neuropathy, causes deep, persistent itching. These symptoms aren’t just superficial: they result from nerve malfunctions that fail to communicate properly with the brain. Repeated scratching damages the skin, increasing the risk of infection. If left untreated, this can lead to serious complications, such as ulcers and, in extreme cases, even amputations.
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Biliary cirrhosis: Intense nocturnal itching
Another cause of persistent itchy hands and feet is biliary cirrhosis, a little-known but serious liver disease. This condition, which primarily affects the liver’s bile ducts, causes bile to accumulate, leading to progressive liver damage. Itching caused by biliary cirrhosis is often more intense at night and can become unbearable for the sufferer. In addition to itching, biliary cirrhosis can also present other symptoms, such as extreme fatigue, dark urine, dry mouth and eyes, and digestive discomfort.
This type of cirrhosis progresses slowly, and its early symptoms are often ignored or attributed to simple skin problems. However, prompt treatment and continued medical care are essential to avoid irreversible liver failure.
2. Itchy eyes: a warning sign for the liver
